PTGX — Protagonist Therapeutics, Inc. stock price, charts and financials

QT68Protagonist Therapeutics, Inc.

Protagonist Therapeutics, Inc. (NASDAQ: PTGX) is a Healthcare company in the Biotechnology industry. QuoTrend tracks its price, financials, earnings, analyst ratings and insider trades.

Latest market price
143.70
+0.86+0.60%
PTGXQT68Protagonist Therapeutics, Inc.·NASDAQ
143.70+0.60%
News
Up 0.6% — Protagonist Therapeutics (NASDAQ:PTGX) Combines High Growth Momentum With a Breakout Setup (ChartMill).
Medium confidence
TA
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Snapshot
Index-P/E139.51EPS (ttm)1.03Insider Own6.89%Shs Outstand64.31MPerf Week-1.01%
Market Cap9.24BForward P/E-EPS next Y-0.49Insider Trans-11.43%Shs Float52.49MPerf Month-8.67%
Enterprise Value8.47BPEG11.95EPS next Q2.43Inst Own-Short Float14.69%Perf Quarter28.95%
Income84.00MP/S32.89EPS this Y353.42%Inst Trans-Short Ratio11.28Perf Half Y48.01%
Sales281.00MP/B10.98EPS next Y-110.51%ROA9.36%Short Interest7.71MPerf YTD64.53%
Book/sh13.09P/C11.80EPS next 5Y11.67%ROE12.03%52W High160.81 -10.64%Perf Year145.26%
Cash/sh12.18P/FCF72.10EPS past 3/5Y-ROIC6.74%52W Low58.91 143.93%Perf 3Y663.96%
Dividend Est.-EV/EBITDA98.46Sales past 3/5Y19.43% 9.67%Gross Margin99.86%Volatility3.38% 3.73%Perf 5Y213.62%
Dividend TTM-EV/Sales30.13EPS Y/Y TTM-75.65%Oper. Margin20.69%ATR (14)5.46Perf 10Y1037.77%
Dividend Ex-Date-Quick Ratio21.71Sales Y/Y TTM-35.25%Profit Margin29.40%RSI (14)46.34Recom2.00
Dividend Gr. 3/5Y-Current Ratio21.71EPS Q/Q516.36%SMA20-2.66%Beta1.47Target Price169.38
Payout0.00%Debt/Eq0.02Sales Q/Q3450.00%SMA500.12%Rel Volume0.84Prev Close142.84
Employees141LT Debt/Eq0.01EarningsNov 05SMA20032.58%Avg Volume662.32KPrice143.70
IPO DateAug 11, 2016Option/ShortYes / YesEPS/Sales Surpr.2.56% 5.32%Net Debt/EBITDA-4.81Volume558,897Change0.60%
Analyst Ratings
DateActionAnalystRatingTarget
Sep-01-26ReiteratedBarclaysOverweight$153$180
Sep-01-26ReiteratedBMO CapitalOutperform$178$190
Aug-31-26ReiteratedHC Wainwright & Co.Buy$117$170
Aug-17-26ReiteratedBMO CapitalOutperform$62$178
Aug-10-26UpgradeGoldman SachsNeutralBuy$110$186
Aug-10-26ReiteratedTruist SecuritiesBuy$145$170
Aug-10-26ReiteratedWedbushOutperform$70$173
Aug-06-26ReiteratedBarclaysOverweight$151$153
Jul-17-26ReiteratedJohnson Rice$137$165
Jul-14-26ReiteratedBarclaysOverweight$108$151
Latest News· Times ET
Sep-15-26
Sep-13-26
Sep-11-26
Sep-09-26
Sep-08-26
Sep-06-26
Sep-02-26
Sep-01-26
Aug-31-26
Aug-28-26
Aug-27-26
Company

Protagonist Therapeutics, Inc. is a biopharmaceutical firm dedicated to discovering and advancing peptide-based therapies. Their research primarily focuses on treatments for hematological and blood conditions, as well as inflammatory and immune-mediated disorders. The company's pipeline features rusfertide (PTG-300), an injectable hepcidin mimetic currently undergoing Phase II clinical trials for the management of polycythemia vera, hereditary hemochromatosis, and other blood-related ailments. Also in Phase II development is PN-943, an oral peptide engineered as a specific antagonist of alpha-4-beta-7 integrin, intended for addressing inflammatory bowel disease (IBD). Furthermore, they are progressing PN-235, an orally administered antagonist specifically targeting the interleukin-23 receptor, designed for both IBD and various non-IBD therapeutic applications. Protagonist Therapeutics maintains a licensing and collaborative agreement with Janssen Biotech, Inc. Founded in 2006, the company's headquarters are located in Newark, California.

Ownership

Per-holder 13F data hasn't been ingested for this ticker yet.

Financial Statements
DataTimeframe
Line Item (USD, M)
TTM
FY 2025
12/31/2025
FY 2024
12/31/2024
FY 2023
12/31/2023
FY 2022
12/31/2022
FY 2021
12/31/2021
FY 2020
12/31/2020
FY 2019
12/31/2019
FY 2018
12/31/2018
Total Revenue28146434
Cost of Goods Sold Incl. D&A010
Gross Profit28145434
Selling, General and Administrative Excl. Other484543
Research and Development175159138
Other Operating Expense1-11
Operating Income59-158253
Interest Expense
000
Unusual Expense
Non-Operating Income (Expense)262927
Net Income Before Taxes84-129279
Income Taxes114
Consolidated Net Income84-130275
Net Income From Continuing Operations84-130275
Net Income84-130275
EPS (Recurring)1.22-2.054.47
EPS (Basic, Before Extraordinaries)1.22-2.054.47
EPS (Diluted)1.03-2.054.23
EBITDA86-128280
Other After Tax Adjustments
Stock Option Compensation Expense
Price To Earnings Ratio139.519.13
Price To Sales Ratio33.75121.525.51
Gross Margin100.0097.83100.00
Operating Margin21.00-343.4858.29
Net Margin29.89-282.6163.36
Shares Outstanding666462
Market Capitalization9,4845,5902,393
Operating Lease Expense
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Insider Trading Volume
$174.77$139.78$104.79$69.80$34.81 Close Price0.00M4.56M9.12M13.68M18.24MUSD Trades VolumeSepOctNovDec2026FebMarAprMayJunJulAugSep
Insider Trading
InsiderRelationshipDateTransactionCost#SharesValue ($)#Shares TotalSEC Form 4
PATEL DINESH V PH DPresident and CEOSep 10 '26Option Exercise21.587,278157,059530,246Sep 10
PATEL DINESH V PH DPresident and CEOSep 10 '26Sale144.107,2781,048,760522,968Sep 10
PATEL DINESH V PH DPresident and CEOSep 09 '26Option Exercise21.5863,5481,371,366586,516Sep 10
PATEL DINESH V PH DPresident and CEOSep 09 '26Sale146.1863,5489,289,447522,968Sep 10
PATEL DINESH V PH DPresident and CEOSep 08 '26Sale145.8754,1747,902,361522,968Sep 10
PATEL DINESH V PH DPresident and CEOSep 08 '26Option Exercise21.5854,1741,169,075577,142Sep 10
PATEL DINESH V PH DPresident and CEOAug 11 '26Option Exercise21.5834,239738,878557,717Aug 12
PATEL DINESH V PH DPresident and CEOAug 11 '26Sale148.5234,2395,085,176523,478Aug 12
PATEL DINESH V PH DPresident and CEOAug 10 '26Option Exercise21.5865,7611,419,122589,239Aug 12
PATEL DINESH V PH DPresident and CEOAug 10 '26Sale149.1165,7619,805,623523,478Aug 12
Waddill William D.DirectorJun 23 '26Option Exercise16.549,000148,86016,825Jun 25
Waddill William D.DirectorJun 23 '26Sale117.949,0001,061,4607,825Jun 25
Waddill William D.DirectorJun 10 '26Option Exercise14.969,000134,64016,825Jun 11
Waddill William D.DirectorJun 10 '26Sale107.689,000969,1207,825Jun 11
Waddill William D.DirectorMay 29 '26Option Exercise11.809,000106,20016,825Jun 01
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