PRAX — Praxis Precision Medicines, Inc. stock price, charts and financials

QT91Praxis Precision Medicines, Inc.

Praxis Precision Medicines, Inc. (NASDAQ: PRAX) is a Healthcare company in the Biotechnology industry. QuoTrend tracks its price, financials, earnings, analyst ratings and insider trades.

Latest market price
310.07
+4.56+1.49%
PRAXQT91Praxis Precision Medicines, Inc.·NASDAQ
310.07+1.49%
Earnings
Up 1.5% — Earnings due 2026-08-06 — pre-report positioning.
Medium confidence
TA
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Snapshot
Index-P/E-EPS (ttm)-Insider Own-Shs Outstand27.88MPerf Week4.82%
Market Cap8.64BForward P/E-EPS next Y-10.40Insider Trans-0.05%Shs Float26.12MPerf Month-1.09%
Enterprise Value8.29BPEG-EPS next Q-Inst Own-Short Float14.41%Perf Quarter-8.16%
Income-303.00MP/S0.00EPS this Y-Inst Trans-Short Ratio7.54Perf Half Y0.31%
Sales0.00P/B20.63EPS next Y31.89%ROA-22.36%Short Interest3.76MPerf YTD5.20%
Book/sh15.03P/C24.56EPS next 5Y-ROE-43.02%52W High366.51 -15.40%Perf Year473.25%
Cash/sh12.63P/FCF-EPS past 3/5Y-ROIC-25.32%52W Low37.19 733.75%Perf 3Y2009.32%
Dividend Est.-EV/EBITDA-Sales past 3/5Y-Gross Margin0.00%Volatility5.13% 5.61%Perf 5Y31.66%
Dividend TTM-EV/Sales0.00EPS Y/Y TTM-30.95%Oper. Margin0.00%ATR (14)18.07Perf 10Y-
Dividend Ex-Date-Quick Ratio15.88Sales Y/Y TTM-Profit Margin0.00%RSI (14)49.65Recom2.31
Dividend Gr. 3/5Y-Current Ratio15.88EPS Q/Q2.74%SMA20-1.41%Beta2.74Target Price578.86
Payout0.00%Debt/Eq0.00Sales Q/Q-SMA501.32%Rel Volume0.68Prev Close305.51
Employees168LT Debt/Eq0.01EarningsAug 06SMA2008.05%Avg Volume482.27KPrice310.07
IPO DateOct 16, 2020Option/ShortYes / YesEPS/Sales Surpr.10.85% -Net Debt/EBITDA1.64Volume326,888Change1.49%
Analyst Ratings
DateActionAnalystRatingTarget
Jul-13-26InitiatedGoldman SachsBuy$447
Jun-29-26ReiteratedNeedhamBuy$510$575
Jun-17-26InitiatedRBC CapitalOutperform$449
Jun-02-26ReiteratedRobert W. Baird$433$400
Jun-02-26ReiteratedBTIGBuy$843$810
Jun-02-26ReiteratedHC Wainwright & Co.Buy$1201
Jun-02-26ReiteratedTruist SecuritiesBuy$715$616
Jun-02-26ReiteratedDeutsche BankBuy$420$374
Jun-02-26ReiteratedWedbushUnderperform$166$162
Jun-02-26ReiteratedOppenheimerOutperform$750$650
Latest News
Aug-04-26
Jul-30-26
Jul-29-26
Jul-28-26
Jul-26-26
Jul-22-26
Jul-13-26
Jul-07-26
Jul-02-26
Jun-29-26
Jun-23-26
Jun-22-26
Company

Praxis Precision Medicines, Inc. is a biopharmaceutical firm operating at the clinical stage, dedicated to creating innovative treatments for central nervous system (CNS) conditions that stem from an imbalance in neuronal activity. The company's primary investigational compounds currently undergoing evaluation include: PRAX-114, an extrasynaptic-preferring positive allosteric modulator of the GABAA receptor, which is currently in Phase IIa clinical trials for addressing both major depressive disorder and perimenopausal depression. Additionally, PRAX-944, a small molecule designed to selectively inhibit T-type calcium channels, is also progressing through Phase IIa clinical trials to manage essential tremor. Beyond these, Praxis is also advancing a pipeline of other promising drug candidates, such as: PRAX-562, a persistent sodium current blocker, undergoing Phase I clinical evaluation for treating severe pediatric epilepsy and adult cephalgia (headaches). PRAX-222, an antisense oligonucleotide (ASO) aimed at individuals suffering from gain-of-function (GOF) SCN2A epilepsy. And a program targeting KCNT1 for the treatment of KCNT1 GOF epilepsy. To further its research and development efforts, Praxis maintains several strategic alliances. These include a cooperation and licensing arrangement with RogCon Inc.; a licensing deal with Purdue Neuroscience Company; a comprehensive research collaboration, option, and license agreement with Ionis Pharmaceuticals, Inc.; and a collaborative project with The Florey Institute focused on the creation of three new antisense oligonucleotides (ASOs). Established in 2015, the company's headquarters are situated in Boston, Massachusetts.

Ownership

Per-holder 13F data hasn't been ingested for this ticker yet.

Financial Statements
DataTimeframe
Line Item (USD, M)
FY 2025
12/31/2025
FY 2024
12/31/2024
FY 2023
12/31/2023
FY 2022
12/31/2022
FY 2021
12/31/2021
FY 2020
12/31/2020
FY 2019
12/31/2019
FY 2018
12/31/2018
Total Revenue09200000
Cost of Goods Sold Incl. D&A0152871540010
Gross Profit0-144-84-15400-10
Selling, General and Administrative Excl. Other59564260471764
Research and Development26715287155120453019
Other Operating Expense0-152-87-1540000
Operating Income-326-200-126-215-167-62-36-23
Interest Expense
00000000
Unusual Expense
Non-Operating Income (Expense)231731000-4
Net Income Before Taxes-303-183-123-214-167-62-36-26
Income Taxes
00000000
Consolidated Net Income-303-183-123-214-167-62-36-27
Net Income From Continuing Operations-303-183-123-214-167-62-36-27
Net Income-303-183-123-214-167-62-36-27
EPS (Recurring)-13.48-10.21-18.69-69.33-58.96-103.61-348.24-306.73
EPS (Basic, Before Extraordinaries)-13.48-10.21-18.69-69.33-58.96-103.61-348.24-306.73
EPS (Diluted)-13.48-10.21-18.69-69.33-58.96-103.61-348.24-306.73
EBITDA-303-182-123-214-167-62-35-26
Other After Tax Adjustments
Stock Option Compensation Expense
Price To Earnings Ratio
Price To Sales Ratio153.9277.98
Gross Margin-1,600.00-4,200.00
Operating Margin-2,222.22-6,300.00
Net Margin-2,033.33-6,150.00
Shares Outstanding2318733100
Market Capitalization6,7791,385156107887825
Operating Lease Expense
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Insider Trading Volume
$405.28$300.95$196.62$92.28$-12.05 Close Price0.00M8.30M16.60M24.90M33.20MUSD Trades VolumeAugSepOctNovDec2026FebMarAprMayJunJulAug
Insider Trading
InsiderRelationshipDateTransactionCost#SharesValue ($)#Shares TotalSEC Form 4
DeSimone JillDirectorJun 24 '26Option Exercise71.2011,600825,95413,937Jun 26
DeSimone JillDirectorJun 24 '26Sale311.3211,6003,611,3342,337Jun 26
Nemiroff AlexGeneral Counsel and SecretaryNov 20 '25Sale193.0925,1304,852,25620,832Nov 21
Nemiroff AlexGeneral Counsel and SecretaryNov 20 '25Option Exercise73.7625,1301,853,53245,962Nov 21
Mastrocola LaurenPrincipal Accounting OfficerNov 20 '25Option Exercise61.1213,600831,25824,042Nov 21
Mastrocola LaurenPrincipal Accounting OfficerNov 20 '25Sale192.0813,6002,612,24410,442Nov 21
Adage Capital Management, L.P.10% OwnerOct 16 '25Sale105.76313,91033,198,1242,060,175Oct 17
MITCHELL DEAN JDirectorSep 24 '25Option Exercise39.5112,251483,99217,251Sep 25
Mastrocola LaurenPrincipal Accounting OfficerNov 14 '24Sale81.785,188424,3185,613Nov 15
Nemiroff AlexGeneral Counsel and SecretaryNov 14 '24Option Exercise56.947,583431,77618,540Nov 15
Nemiroff AlexGeneral Counsel and SecretaryNov 14 '24Sale80.208,239660,82710,301Nov 15
Mastrocola LaurenPrincipal Accounting OfficerNov 14 '24Option Exercise56.944,374249,05610,801Nov 15
DeSimone JillDirectorOct 05 '23Buy1.7514,50025,37514,500Oct 10
Souza MarcioChief Executive OfficerJun 27 '23Buy1.0610,00010,58745,002Jun 27
Kelly Timothy EdwinChief Financial OfficerMar 24 '23Buy0.8716,00013,99646,416Apr 06
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