Zymeworks Inc. (NASDAQ: ZYME) is a Healthcare company in the Biotechnology industry. QuoTrend tracks its price, financials, earnings, analyst ratings and insider trades.
| Index | - | P/E | - | EPS (ttm) | -1.37 | Insider Own | 48.84% | Shs Outstand | 73.57M | Perf Week | 0.80% |
| Market Cap | 1.68B | Forward P/E | 17.41 | EPS next Y | 1.31 | Insider Trans | 0.00% | Shs Float | 68.01M | Perf Month | -10.03% |
| Enterprise Value | 1.33B | PEG | - | EPS next Q | - | Inst Own | - | Short Float | 6.03% | Perf Quarter | -14.90% |
| Income | -103.00M | P/S | 20.45 | EPS this Y | 195.60% | Inst Trans | - | Short Ratio | 6.22 | Perf Half Y | -1.64% |
| Sales | 82.00M | P/B | 10.22 | EPS next Y | -0.07% | ROA | -21.47% | Short Interest | 4.10M | Perf YTD | -13.44% |
| Book/sh | 2.23 | P/C | 4.59 | EPS next 5Y | -7.28% | ROE | -37.79% | 52W High | 29.75 -23.39% | Perf Year | 81.30% |
| Cash/sh | 4.96 | P/FCF | - | EPS past 3/5Y | - | ROIC | -25.26% | 52W Low | 11.51 98.00% | Perf 3Y | 213.48% |
| Dividend Est. | - | EV/EBITDA | - | Sales past 3/5Y | -36.40% 22.14% | Gross Margin | 94.42% | Volatility | 4.69% 3.93% | Perf 5Y | -33.11% |
| Dividend TTM | - | EV/Sales | 16.20 | EPS Y/Y TTM | 15.43% | Oper. Margin | -140.35% | ATR (14) | 1.02 | Perf 10Y | - |
| Dividend Ex-Date | - | Quick Ratio | 10.82 | Sales Y/Y TTM | 7.89% | Profit Margin | -126.33% | RSI (14) | 43.89 | Recom | 2.10 |
| Dividend Gr. 3/5Y | - | Current Ratio | 10.82 | EPS Q/Q | -96.67% | SMA20 | -4.30% | Beta | 1.13 | Target Price | 40.50 |
| Payout | 0.00% | Debt/Eq | 0.06 | Sales Q/Q | -92.59% | SMA50 | -5.55% | Rel Volume | 0.67 | Prev Close | 21.81 |
| Employees | 264 | LT Debt/Eq | 0.06 | Earnings | Aug 06 | SMA200 | -5.13% | Avg Volume | 623.69K | Price | 22.79 |
| IPO Date | Apr 28, 2017 | Option/Short | Yes / Yes | EPS/Sales Surpr. | -98.77% -90.12% | Net Debt/EBITDA | 2.41 | Volume | 419,785 | Change | 4.49% |
| Date | Action | Analyst | Rating | Target |
|---|---|---|---|---|
| Jul-07-26 | Reiterated | Truist Securities | Buy | $28 → $31 |
| Jun-30-26 | Reiterated | Wells Fargo | Overweight | $33 → $37 |
| Jun-09-26 | Reiterated | Truist Financial | $40 → $28 | |
| Jun-03-26 | Reiterated | HC Wainwright & Co. | Buy | $26 → $46 |
| Mar-09-26 | Reiterated | Evercore ISI Group | Outperform | $48 |
| Dec-17-25 | Initiated | Truist | Buy | $40 |
| Dec-12-25 | Upgrade | Wells Fargo | Equal Weight → Overweight | $25 → $33 |
| Dec-03-25 | Initiated | Citizens JMP | Outperform | $32 |
| Nov-19-25 | Reiterated | Stifel Nicolaus | Buy | $28 → $40 |
| Nov-19-25 | Reiterated | Wells Fargo | Equal Weight | $12 → $25 |
Zymeworks Inc. is a biopharmaceutical firm in the clinical development phase, dedicated to identifying, advancing, and bringing to market biological therapies aimed at combating cancer. Its pipeline features two primary experimental treatments: zanidatamab, a cutting-edge bispecific antibody currently undergoing Phase 1 and Phase 2 studies for various malignancies such as those affecting the biliary tract, gastroesophageal region (adenocarcinomas), breast, and colon; and ZW49, an antibody-drug conjugate targeting two sites on the human epidermal growth factor receptor 2 (HER2), which is in Phase 1 trials for advanced or spreading tumors that express HER2. Zymeworks maintains significant alliances with several pharmaceutical leaders, including Merck Sharp & Dohme Research Ltd., Eli Lilly and Company, Bristol-Myers Squibb company, GlaxoSmithKline Intellectual Property Development Ltd., Daiichi Sankyo Co., Ltd., Janssen Biotech, Inc., BeiGene, Ltd., and Exelixis, Inc. Furthermore, it engages in cooperative research and licensing agreements with LEO Pharma A/S, specifically for the exploration, advancement, and market introduction of bispecific antibodies, and with Iconic Therapeutics, Inc. Established in 2003, Zymeworks Inc. operates from its headquarters located in Vancouver, Canada.
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| Line Item (USD, M) | TTM — | FY 2025 12/31/2025 | FY 2024 12/31/2024 | FY 2023 12/31/2023 | FY 2022 12/31/2022 | FY 2021 12/31/2021 | FY 2020 12/31/2020 | FY 2019 12/31/2019 | FY 2018 12/31/2018 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Total Revenue | 82 | 106 | 76 | 76 | 412 | 27 | 39 | 30 | 53 | |
| Cost of Goods Sold Incl. D&A | 5 | 0 | 0 | 143 | 0 | 0 | 171 | 117 | 57 | |
| Gross Profit | 78 | 106 | 76 | -67 | 412 | 27 | -132 | -88 | -4 | |
| Selling, General and Administrative Excl. Other | 15,112 | 62 | 62 | 70 | 73 | 43 | 55 | 63 | 29 | |
| Research and Development | 2,509 | 137 | 135 | 144 | 209 | 200 | 171 | 118 | 57 | |
| Other Operating Expense | -17,430 | 0 | 16 | -143 | 0 | -1 | -170 | -117 | 0 | |
| Operating Income | -114 | -93 | -137 | -138 | 131 | -216 | -187 | -151 | -33 | |
| Interest Expense | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Unusual Expense | — | — | — | — | — | — | — | — | — | |
| Non-Operating Income (Expense) | 13 | 13 | 20 | 19 | 5 | 3 | 7 | 6 | -1 | |
| Net Income Before Taxes | -103 | -80 | -117 | -119 | 135 | -212 | -180 | -145 | -34 | |
| Income Taxes | -1 | 1 | 6 | -1 | 11 | -1 | 0 | 1 | 2 | |
| Consolidated Net Income | -103 | -81 | -123 | -119 | 124 | -212 | -181 | -145 | -37 | |
| Net Income From Continuing Operations | -103 | -81 | -123 | -119 | 124 | -212 | -181 | -145 | -37 | |
| Net Income | -103 | -81 | -123 | -119 | 124 | -212 | -181 | -145 | -37 | |
| EPS (Recurring) | -1.37 | -1.08 | -1.62 | -1.72 | 1.91 | -4.06 | -3.58 | -3.83 | -1.26 | |
| EPS (Basic, Before Extraordinaries) | -1.37 | -1.08 | -1.62 | -1.72 | 1.91 | -4.06 | -3.58 | -3.83 | -1.26 | |
| EPS (Diluted) | -1.37 | -1.08 | -1.62 | -1.72 | 1.90 | -4.61 | -3.58 | -3.83 | -1.26 | |
| EBITDA | -94 | -69 | -109 | -121 | 142 | -206 | -184 | -148 | -31 | |
| Other After Tax Adjustments | — | — | — | — | — | — | — | — | — | |
| Stock Option Compensation Expense | — | — | — | — | — | — | — | — | — | |
| Price To Earnings Ratio | — | — | — | — | 4.14 | — | — | — | — | |
| Price To Sales Ratio | 20.84 | 18.63 | 14.64 | 9.43 | 1.24 | 31.57 | 60.59 | 57.58 | 8.03 | |
| Gross Margin | 95.12 | 100.00 | 100.00 | -88.16 | 100.00 | 100.00 | -338.46 | -293.33 | -7.55 | |
| Operating Margin | -139.02 | -87.74 | -180.26 | -181.58 | 31.80 | -800.00 | -479.49 | -503.33 | -62.26 | |
| Net Margin | -125.61 | -76.42 | -161.84 | -156.58 | 30.10 | -785.19 | -464.10 | -483.33 | -69.81 | |
| Shares Outstanding | 75 | 75 | 76 | 69 | 65 | 52 | 50 | 38 | 29 | |
| Market Capitalization | 1,709 | 1,975 | 1,113 | 717 | 511 | 852 | 2,363 | 1,727 | 426 | |
| Operating Lease Expense | — | — | — | — | — | — | — | — | — |
| Insider | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|
| Hollywood Mark | EVP & Chief Operating Officer | Jan 12 '26 | Option Exercise | 0.00 | 17,666 | 0 | 139,033 | Jan 13 |
| Hollywood Mark | EVP & Chief Operating Officer | Jan 12 '26 | Sale | 22.67 | 6,120 | 138,762 | 132,913 | Jan 13 |
| Smith Jeffrey T L | EVP & Chief Medical Officer | Jan 12 '26 | Option Exercise | 0.00 | 17,666 | 0 | 36,018 | Jan 12 |
| Smith Jeffrey T L | EVP & Chief Medical Officer | Jan 12 '26 | Sale | 22.67 | 9,310 | 211,090 | 26,708 | Jan 12 |
| Moore Paul Andrew | Chief Scientific Officer | Jan 12 '26 | Option Exercise | 0.00 | 17,666 | 0 | 58,057 | Jan 12 |
| Moore Paul Andrew | Chief Scientific Officer | Jan 12 '26 | Sale | 22.67 | 9,560 | 216,759 | 48,497 | Jan 12 |
| Galbraith Kenneth | Chair & CEO | Jan 12 '26 | Option Exercise | 0.00 | 64,000 | 0 | 257,266 | Jan 12 |
| Galbraith Kenneth | Chair & CEO | Jan 12 '26 | Sale | 22.67 | 30,424 | 689,819 | 226,842 | Jan 12 |
| Smith Jeffrey T L | EVP & Chief Medical Officer | Jan 05 '26 | Option Exercise | 0.00 | 20,000 | 0 | 28,890 | Jan 05 |
| Smith Jeffrey T L | EVP & Chief Medical Officer | Jan 05 '26 | Sale | 25.10 | 10,538 | 264,471 | 18,352 | Jan 05 |
| Galbraith Kenneth | Chair & CEO | Jan 05 '26 | Option Exercise | 0.00 | 114,334 | 0 | 224,952 | Jan 05 |
| Galbraith Kenneth | Chair & CEO | Jan 05 '26 | Sale | 25.10 | 54,343 | 1,363,840 | 158,286 | Jan 05 |
| Moore Paul Andrew | Chief Scientific Officer | Jan 05 '26 | Option Exercise | 0.00 | 37,168 | 0 | 51,212 | Jan 05 |
| Moore Paul Andrew | Chief Scientific Officer | Jan 05 '26 | Sale | 25.10 | 20,110 | 504,699 | 31,212 | Jan 05 |
| Galbraith Kenneth | Chair & CEO | Dec 22 '25 | Option Exercise | 0.00 | 100,000 | 0 | 180,803 | Dec 22 |