BeOne Medicines AG (NASDAQ: ONC) is a Healthcare company in the Biotechnology industry. QuoTrend tracks its price, financials, earnings, analyst ratings and insider trades.
| Index | - | P/E | 4.74 | EPS (ttm) | 66.70 | Insider Own | 24.12% | Shs Outstand | 106.86M | Perf Week | -3.03% |
| Market Cap | 39.82B | Forward P/E | 32.20 | EPS next Y | 9.81 | Insider Trans | -2.74% | Shs Float | 67.18M | Perf Month | 8.69% |
| Enterprise Value | 37.03B | PEG | 0.01 | EPS next Q | - | Inst Own | - | Short Float | 1.38% | Perf Quarter | 7.02% |
| Income | 374.32M | P/S | 6.90 | EPS this Y | -85.26% | Inst Trans | - | Short Ratio | 3.40 | Perf Half Y | -9.71% |
| Sales | 5.77B | P/B | 11.50 | EPS next Y | 43.27% | ROA | 6.00% | Short Interest | 926.99K | Perf YTD | 4.02% |
| Book/sh | - | P/C | 42.48 | EPS next 5Y | 33.04% | ROE | 12.10% | 52W High | 382.51 -17.97% | Perf Year | 5.36% |
| Cash/sh | - | P/FCF | 36.12 | EPS past 3/5Y | - | ROIC | 7.74% | 52W Low | 252.15 24.44% | Perf 3Y | 55.93% |
| Dividend Est. | - | EV/EBITDA | 43.97 | Sales past 3/5Y | 55.68% 76.83% | Gross Margin | 87.17% | Volatility | 2.24% 2.54% | Perf 5Y | -0.29% |
| Dividend TTM | - | EV/Sales | 6.42 | EPS Y/Y TTM | 859.31% | Oper. Margin | 11.96% | ATR (14) | 9.06 | Perf 10Y | 1043.72% |
| Dividend Ex-Date | - | Quick Ratio | 3.27 | Sales Y/Y TTM | 50.60% | Profit Margin | 8.93% | RSI (14) | 55.56 | Recom | 2.00 |
| Dividend Gr. 3/5Y | - | Current Ratio | 3.64 | EPS Q/Q | 60.66% | SMA20 | 0.38% | Beta | 0.50 | Target Price | 396.89 |
| Payout | 0.00% | Debt/Eq | 0.43 | Sales Q/Q | 35.45% | SMA50 | 7.30% | Rel Volume | 0.81 | Prev Close | 316.01 |
| Employees | 12,000 | LT Debt/Eq | 0.43 | Earnings | Aug 05 | SMA200 | 0.63% | Avg Volume | 308.11K | Price | 313.77 |
| IPO Date | Feb 03, 2016 | Option/Short | Yes / Yes | EPS/Sales Surpr. | 82.22% 5.35% | Net Debt/EBITDA | -3.31 | Volume | 249,900 | Change | -0.71% |
| Date | Action | Analyst | Rating | Target |
|---|---|---|---|---|
| Jul-14-26 | Reiterated | Barclays | Overweight | $409 → $403 |
| Jul-13-26 | Upgrade | Jefferies | Hold → Buy | $420 → $380 |
| Jul-07-26 | Reiterated | RBC Capital | Outperform | $436 → $451 |
| Jul-07-26 | Reiterated | Truist Securities | Buy | $411 → $416 |
| Jun-02-26 | Reiterated | RBC Capital | Outperform | $425 → $436 |
| May-15-26 | Reiterated | Leerink Partners | Outperform | $367 |
| May-07-26 | Reiterated | Morgan Stanley | Overweight | $389 → $395 |
| May-07-26 | Reiterated | Barclays | Overweight | $394 → $409 |
| May-07-26 | Reiterated | Guggenheim | Buy | $420 |
| May-04-26 | Initiated | Wells Fargo | Overweight | $400 |
BeOne Medicines AG, an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company’s commercial stage products include BRUKINSA, a small molecule inhibitor of Bruton’s Tyrosine Kinase (BTK) for the treatment of various blood cancers; TEVIMBRA, an anti-PD-1 antibody immunotherapy for the treatment of various solid tumor and blood cancers; SYLVANT for the treatment of adult patients with multicentric castleman disease; BAITUOWEI for patients with BC in premenopausal and perimenopausal women, and cancer; and PARTRUVIX for the treatment of various solid tumors. Its clinical stage products comprise Sonrotoclax BGB-11417, a small molecule Bcl-2 inhibitor; BGB-16673, a BTK targeting chimeric degradation activation compound active against wild type and mutant BTK; BG-60366, an EGFR-targeted CDAC; BG-89894 (SYH2039), a MAT2A Inhibitor; BGB-58067, an MTA-Cooperative PRMT5 Inhibitor; BG-T187 and BG-C0902, an anti-EGFRxMET trispecific antibody; BGB-26808, a HPK-1 Inhibitor; BGB-C354, an anti-B7H3 ADC; Zanidatamab, a bispecific HER2-targeted antibody; BG-C137, an anti-FGFR2b ADC; BGB-53038, a Pan-KRAS Inhibitor; BGB-B2033, an anti-GPC3x4-1BB bispecific antibody; BGB-B3227, an anti-MUC1xCD16A bispecific antibody; BG-C477, an anti-CEAADC; BGB-43395, a CDK4 Inhibitor; BG-68501, a CDK2 Inhibitor; BG-C9074, an anti-B7H4 ADC; BGB-21447, a Bcl-2 Inhibitor; and BGB-45035, an IRAK4-targeted CDAC. It also has various preclinical programs. The company has agreements Amgen, BMS, Bio-Thera, EUSA Pharma, Luye Pharmaceutical, and Novartis. The company was formerly known as BeiGene, Ltd. and changed its name to BeOne Medicines AG in May 2025. BeOne Medicines AG was founded in 2010 and is based in Basel, Switzerland.
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| Line Item (USD, M) | TTM — | FY 2025 12/31/2025 | FY 2024 12/31/2024 | FY 2023 12/31/2023 | FY 2022 12/31/2022 | FY 2021 12/31/2021 | FY 2020 12/31/2020 | FY 2019 12/31/2019 | FY 2018 12/31/2018 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Total Revenue | 5,738 | 5,343 | 3,810 | 2,459 | 1,416 | 1,176 | 309 | 428 | 198 | |
| Cost of Goods Sold Incl. D&A | 671 | 669 | 594 | 380 | 286 | 165 | 71 | 71 | 708 | |
| Gross Profit | 5,069 | 4,674 | 3,216 | 2,079 | 1,129 | 1,011 | 238 | 357 | -509 | |
| Selling, General and Administrative Excl. Other | 2,177 | 2,081 | 1,831 | 1,508 | 1,279 | 990 | 600 | 388 | 195 | |
| Research and Development | 2,205 | 2,146 | 1,953 | 1,779 | 1,641 | 1,459 | 1,295 | 927 | 679 | |
| Other Operating Expense | 1 | 0 | 0 | 0 | -1 | 1 | 1 | 2 | -678 | |
| Operating Income | 686 | 447 | -568 | -1,208 | -1,790 | -1,439 | -1,658 | -960 | -706 | |
| Interest Expense | 33 | 58 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Unusual Expense | — | — | — | — | — | — | — | — | — | |
| Non-Operating Income (Expense) | 2 | 28 | 35 | 382 | -171 | 0 | 39 | 16 | 16 | |
| Net Income Before Taxes | 655 | 417 | -533 | -826 | -1,961 | -1,439 | -1,618 | -944 | -690 | |
| Income Taxes | 142 | 130 | 112 | 56 | 43 | 19 | 10 | 7 | -16 | |
| Consolidated Net Income | 513 | 287 | -645 | -882 | -2,004 | -1,458 | -1,625 | -949 | -674 | |
| Net Income From Continuing Operations | 513 | 287 | -645 | -882 | -2,004 | -1,458 | -1,629 | -951 | -674 | |
| Net Income | 513 | 287 | -645 | -882 | -2,004 | -1,458 | -1,625 | -949 | -674 | |
| EPS (Recurring) | 49.88 | 33.80 | -6.12 | -8.45 | -19.37 | -15.21 | -19.11 | -15.86 | -12.09 | |
| EPS (Basic, Before Extraordinaries) | 49.88 | 33.80 | -6.12 | -8.45 | -19.37 | -15.21 | -19.11 | -15.86 | -12.09 | |
| EPS (Diluted) | 46.47 | 32.11 | -6.12 | -8.45 | -19.37 | -15.21 | -19.11 | -15.86 | -12.09 | |
| EBITDA | 901 | 617 | -361 | -738 | -1,895 | -1,392 | -1,626 | -941 | -695 | |
| Other After Tax Adjustments | — | — | — | — | — | — | — | — | — | |
| Stock Option Compensation Expense | — | — | — | — | — | — | — | — | — | |
| Price To Earnings Ratio | 6.75 | 9.46 | — | — | — | — | — | — | — | |
| Price To Sales Ratio | 6.07 | 6.20 | 5.09 | 7.63 | 16.00 | 21.43 | 69.41 | 23.24 | 38.96 | |
| Gross Margin | 88.34 | 87.48 | 84.41 | 84.55 | 79.73 | 85.97 | 77.02 | 83.41 | -257.07 | |
| Operating Margin | 11.96 | 8.37 | -14.91 | -49.13 | -126.41 | -122.36 | -536.57 | -224.30 | -356.57 | |
| Net Margin | 8.94 | 5.37 | -16.93 | -35.87 | -141.53 | -123.98 | -525.89 | -221.73 | -340.40 | |
| Shares Outstanding | 111 | 109 | 105 | 104 | 103 | 93 | 83 | 60 | 55 | |
| Market Capitalization | 34,828 | 33,115 | 19,395 | 18,757 | 22,654 | 25,196 | 21,446 | 9,946 | 7,714 | |
| Operating Lease Expense | — | — | — | — | — | — | — | — | — |
| Insider | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|
| Lee Chan Henry | SVP, General Counsel | Jul 22 '26 | Option Exercise | 27.37 | 23,366 | 639,473 | 98,930 | Jul 24 |
| Lee Chan Henry | SVP, General Counsel | Jul 22 '26 | Sale | 325.00 | 1,669 | 542,425 | 0 | Jul 24 |
| OYLER JOHN | Chief Executive Officer | Jul 21 '26 | Sale | 317.67 | 61,397 | 19,504,058 | 0 | Jul 22 |
| OYLER JOHN | Chief Executive Officer | Jul 20 '26 | Sale | 312.25 | 48,316 | 15,086,798 | 0 | Jul 22 |
| OYLER JOHN | Chief Executive Officer | Jul 20 '26 | Option Exercise | 17.14 | 475,860 | 8,155,900 | 33,990 | Jul 22 |
| OYLER JOHN | Chief Executive Officer | Jul 17 '26 | Option Exercise | 17.14 | 904,792 | 15,507,489 | 441,870 | Jul 17 |
| OYLER JOHN | Chief Executive Officer | Jul 17 '26 | Sale | 312.00 | 64,628 | 20,163,908 | 0 | Jul 17 |
| OYLER JOHN | Chief Executive Officer | Jul 16 '26 | Option Exercise | 20.49 | 2,332,358 | 47,778,985 | 1,282,034 | Jul 17 |
| OYLER JOHN | Chief Executive Officer | Jul 16 '26 | Sale | 318.09 | 166,597 | 52,992,225 | 0 | Jul 17 |
| OYLER JOHN | Chief Executive Officer | Jul 15 '26 | Sale | 311.94 | 116,557 | 36,359,374 | 0 | Jul 17 |
| OYLER JOHN | Chief Executive Officer | Jul 15 '26 | Option Exercise | 21.15 | 1,631,798 | 34,508,630 | 1,254,513 | Jul 17 |
| OYLER JOHN | Chief Executive Officer | Jul 14 '26 | Sale | 305.95 | 145,861 | 44,626,423 | 0 | Jul 14 |
| OYLER JOHN | Chief Executive Officer | Jul 14 '26 | Option Exercise | 7.73 | 1,870,400 | 14,450,042 | 462,866 | Jul 14 |
| OYLER JOHN | Chief Executive Officer | Jul 13 '26 | Sale | 304.35 | 48,520 | 14,766,882 | 0 | Jul 14 |
| OYLER JOHN | Chief Executive Officer | Jul 13 '26 | Option Exercise | 5.27 | 679,280 | 3,581,746 | 1,264,666 | Jul 14 |