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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| ZYME | Smith Jeffrey T L | EVP & Chief Medical Officer | Jan 12 '26 | Option Exercise | 0.00 | 17,666 | 0 | 36,018 | Jan 12 |
| ZYME | Smith Jeffrey T L | EVP & Chief Medical Officer | Jan 12 '26 | Sale | 22.67 | 9,310 | 211,090 | 26,708 | Jan 12 |
| ZYME | Smith Jeffrey T L | EVP & Chief Medical Officer | Jan 05 '26 | Option Exercise | 0.00 | 20,000 | 0 | 28,890 | Jan 05 |
| ZYME | Smith Jeffrey T L | EVP & Chief Medical Officer | Jan 05 '26 | Sale | 25.10 | 10,538 | 264,471 | 18,352 | Jan 05 |
| ZYME | Smith Jeffrey T L | EVP & Chief Medical Officer | Jan 06 '25 | Option Exercise | 0.00 | 20,000 | 0 | 20,000 | Jan 06 |
| ZYME | Smith Jeffrey T L | EVP & Chief Medical Officer | Jan 06 '25 | Sale | 14.92 | 11,110 | 165,807 | 8,890 | Jan 06 |