Smith Jeffrey T L – Insider Transactions

Ticker	Owner	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
ZYME	Smith Jeffrey T L	EVP & Chief Medical Officer	Jan 12 '26	Option Exercise	0.00	35,332	0	36,018	Jan 12 12:00 AM
ZYME	Smith Jeffrey T L	EVP & Chief Medical Officer	Jan 12 '26	Sale	22.67	9,310	211,090	26,708	Jan 12 12:00 AM
ZYME	Smith Jeffrey T L	EVP & Chief Medical Officer	Jan 05 '26	Option Exercise	0.00	40,000	0	28,890	Jan 05 12:00 AM
ZYME	Smith Jeffrey T L	EVP & Chief Medical Officer	Jan 05 '26	Sale	25.10	10,538	264,471	18,352	Jan 05 12:00 AM
ZYME	Smith Jeffrey T L	EVP & Chief Medical Officer	Jan 06 '25	Option Exercise	0.00	40,000	0	40,000	Jan 06 12:00 AM
ZYME	Smith Jeffrey T L	EVP & Chief Medical Officer	Jan 06 '25	Sale	14.92	11,110	165,807	8,890	Jan 06 12:00 AM

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