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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| PTGX | PATEL DINESH V PH D | President and CEO | May 12 '26 | Option Exercise | 21.58 | 150,000 | 3,237,000 | 598,478 | May 12 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | May 12 '26 | Sale | 100.12 | 75,000 | 7,509,000 | 523,478 | May 12 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Mar 25 '26 | Sale | 101.00 | 54,641 | 5,518,741 | 524,938 | Mar 25 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Mar 25 '26 | Option Exercise | 8.58 | 109,282 | 937,640 | 579,579 | Mar 25 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Mar 24 '26 | Option Exercise | 8.58 | 118 | 1,012 | 524,997 | Mar 25 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jan 27 '26 | Sale | 83.19 | 4,068 | 338,417 | 574,505 | Jan 27 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jan 27 '26 | Option Exercise | 21.58 | 8,136 | 175,574 | 578,573 | Jan 27 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jan 26 '26 | Sale | 84.03 | 24,890 | 2,091,470 | 574,505 | Jan 27 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jan 26 '26 | Option Exercise | 14.12 | 49,780 | 703,056 | 588,710 | Jan 27 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jan 23 '26 | Option Exercise | 4.21 | 38,630 | 162,632 | 593,820 | Jan 27 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jan 23 '26 | Sale | 84.59 | 19,315 | 1,633,856 | 574,505 | Jan 27 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jan 20 '26 | Sale | 82.48 | 34,438 | 2,840,446 | 580,505 | Jan 21 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jul 25 '25 | Sale | 54.78 | 10,415 | 570,534 | 520,603 | Jul 28 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jul 23 '25 | Sale | 54.79 | 17,520 | 959,921 | 531,018 | Jul 23 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jul 22 '25 | Sale | 55.05 | 22,065 | 1,214,678 | 548,538 | Jul 23 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jul 21 '25 | Sale | 54.86 | 12,859 | 705,445 | 570,603 | Jul 23 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Mar 05 '25 | Option Exercise | 4.21 | 48,000 | 202,080 | 564,260 | Mar 05 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Feb 19 '25 | Sale | 38.18 | 5,359 | 204,607 | 540,260 | Feb 20 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Nov 26 '24 | Sale | 46.25 | 21,480 | 993,450 | 408,455 | Nov 27 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Nov 25 '24 | Option Exercise | 21.58 | 3,454 | 74,538 | 429,935 | Nov 27 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Nov 25 '24 | Sale | 46.96 | 78,520 | 3,687,299 | 435,208 | Nov 27 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jun 07 '24 | Sale | 35.19 | 35,000 | 1,231,650 | 515,415 | Jun 11 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Apr 01 '24 | Sale | 28.31 | 25,000 | 707,750 | 549,590 | Apr 02 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Mar 01 '24 | Sale | 31.62 | 30,000 | 948,600 | 574,590 | Mar 01 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Dec 13 '23 | Sale | 20.08 | 75,000 | 1,506,000 | 534,347 | Dec 15 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Oct 18 '23 | Option Exercise | 4.21 | 12,000 | 50,520 | 609,347 | Oct 19 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Aug 23 '22 | Option Exercise | 4.21 | 20,000 | 84,200 | 604,048 | Aug 24 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | May 04 '22 | Option Exercise | 0.00 | 15,742 | 0 | 80,000 | May 04 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Apr 26 '22 | Option Exercise | 4.21 | 30,000 | 126,300 | 568,306 | Apr 26 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Apr 14 '22 | Option Exercise | 0.00 | 34,087 | 0 | 0 | Apr 14 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Dec 21 '21 | Sale | 32.14 | 15,000 | 482,171 | 477,158 | Dec 23 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Sep 21 '21 | Option Exercise | 4.21 | 80,000 | 336,800 | 492,158 | Sep 21 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jan 19 '21 | Option Exercise | 4.21 | 26,000 | 109,460 | 450,990 | Jan 20 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jan 19 '21 | Sale | 24.60 | 24,846 | 611,105 | 426,144 | Jan 20 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Mar 20 '20 | Option Exercise | 1.89 | 20,000 | 37,800 | 439,990 | Mar 23 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Mar 12 '20 | Option Exercise | 1.16 | 36,688 | 42,558 | 429,990 | Mar 13 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Dec 03 '19 | Buy | 5.62 | 30,000 | 168,500 | 409,824 | Dec 03 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Nov 26 '19 | Option Exercise | 1.16 | 8,000 | 9,280 | 379,824 | Nov 27 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Aug 06 '19 | Sale | 8.85 | 10,792 | 95,535 | 374,792 | Aug 08 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Mar 01 '19 | Sale | 8.03 | 2,183 | 17,529 | 383,831 | Mar 04 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Feb 06 '19 | Sale | 7.74 | 10,909 | 84,410 | 357,264 | Feb 08 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Jan 11 '19 | Option Exercise | 1.16 | 44,688 | 51,838 | 368,173 | Jan 14 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | May 10 '18 | Option Exercise | 1.16 | 27,032 | 31,358 | 265,779 | May 11 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Apr 02 '18 | Option Exercise | 1.16 | 40,000 | 46,400 | 252,263 | Apr 03 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Mar 26 '18 | Option Exercise | 0.87 | 22,596 | 19,658 | 232,263 | Mar 28 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Dec 21 '17 | Option Exercise | 1.89 | 16,420 | 31,034 | 198,647 | Dec 21 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Dec 21 '17 | Sale | 19.56 | 8,210 | 160,570 | 190,437 | Dec 21 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Dec 20 '17 | Option Exercise | 1.89 | 3,580 | 6,766 | 192,227 | Dec 20 12:00 AM |
| PTGX | PATEL DINESH V PH D | President and CEO | Dec 20 '17 | Sale | 19.55 | 1,790 | 34,987 | 190,437 | Dec 20 12:00 AM |