| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| ONC | OYLER JOHN | Chief Executive Officer | Jul 21 '26 | Sale | 317.67 | 61,397 | 19,504,058 | 0 | Jul 22 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 20 '26 | Sale | 312.25 | 48,316 | 15,086,798 | 0 | Jul 22 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 20 '26 | Option Exercise | 17.14 | 475,860 | 8,155,900 | 33,990 | Jul 22 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 17 '26 | Option Exercise | 17.14 | 904,792 | 15,507,489 | 441,870 | Jul 17 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 17 '26 | Sale | 312.00 | 64,628 | 20,163,908 | 0 | Jul 17 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 16 '26 | Sale | 318.09 | 166,597 | 52,992,225 | 0 | Jul 17 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 16 '26 | Option Exercise | 20.49 | 2,332,358 | 47,778,985 | 1,282,034 | Jul 17 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 15 '26 | Option Exercise | 21.15 | 1,631,798 | 34,508,630 | 1,254,513 | Jul 17 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 15 '26 | Sale | 311.94 | 116,557 | 36,359,374 | 0 | Jul 17 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 14 '26 | Sale | 305.95 | 145,861 | 44,626,423 | 0 | Jul 14 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 14 '26 | Option Exercise | 7.73 | 1,870,400 | 14,450,042 | 462,866 | Jul 14 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 13 '26 | Sale | 304.35 | 48,520 | 14,766,882 | 0 | Jul 14 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 13 '26 | Option Exercise | 5.27 | 679,280 | 3,581,746 | 1,264,666 | Jul 14 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 10 '26 | Sale | 298.34 | 11,698 | 3,489,925 | 0 | Jul 14 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 10 '26 | Option Exercise | 5.27 | 163,772 | 863,546 | 1,895,426 | Jul 14 |
| ONC | OYLER JOHN | Chief Executive Officer | Jun 23 '26 | Sale | 273.78 | 3,410 | 933,592 | 0 | Jun 25 |
| ONC | OYLER JOHN | Chief Executive Officer | Jun 16 '26 | Sale | 265.55 | 3,693 | 980,686 | 0 | Jun 18 |
| ONC | OYLER JOHN | Chief Executive Officer | Jun 11 '26 | Sale | 257.24 | 1,949 | 501,355 | 0 | Jun 15 |
| ONC | OYLER JOHN | Chief Executive Officer | Jun 08 '26 | Sale | 270.56 | 4,940 | 1,336,548 | 0 | Jun 10 |
| ONC | OYLER JOHN | Chief Executive Officer | Dec 16 '25 | Sale | 302.87 | 24,369 | 7,380,741 | 0 | Dec 17 |
| ONC | OYLER JOHN | Chief Executive Officer | Dec 15 '25 | Sale | 307.79 | 75,631 | 23,278,679 | 24,369 | Dec 17 |
| ONC | OYLER JOHN | Chief Executive Officer | Sep 16 '25 | Sale | 325.71 | 27,803 | 9,055,694 | 0 | Sep 18 |
| ONC | OYLER JOHN | Chief Executive Officer | Jul 09 '25 | Sale | 253.38 | 27,802 | 7,044,591 | 0 | Jul 11 |
| ONC | OYLER JOHN | Chief Executive Officer | Jun 23 '25 | Sale | 261.61 | 3,174 | 830,360 | 0 | Jun 25 |
| ONC | OYLER JOHN | Chief Executive Officer | Jun 17 '25 | Sale | 256.49 | 1,460 | 374,473 | 0 | Jun 18 |
| ONC | OYLER JOHN | Chief Executive Officer | Jun 16 '25 | Sale | 266.05 | 3,680 | 979,046 | 1,460 | Jun 18 |
| ONC | OYLER JOHN | Chief Executive Officer | Jun 06 '25 | Sale | 252.77 | 5,127 | 1,295,946 | 0 | Jun 10 |