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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| ALNY | Tanguler Tolga | EVP, Chief Commercial Officer | Mar 04 '26 | Sale | 323.08 | 2,309 | 745,983 | 34,297 | Mar 06 |
| ALNY | Tanguler Tolga | EVP, Chief Commercial Officer | Mar 02 '26 | Sale | 327.65 | 1,598 | 523,584 | 36,606 | Mar 04 |
| ALNY | Tanguler Tolga | EVP, Chief Commercial Officer | Feb 27 '26 | Option Exercise | 0.00 | 1,666 | 0 | 33,435 | Mar 02 |
| ALNY | Tanguler Tolga | EVP, Chief Commercial Officer | Feb 13 '26 | Sale | 310.08 | 1,959 | 607,448 | 31,769 | Feb 17 |
| ALNY | Tanguler Tolga | EVP, Chief Commercial Officer | Jan 12 '26 | Sale | 362.87 | 1,510 | 547,927 | 29,728 | Jan 14 |
| ALNY | Tanguler Tolga | EVP, Chief Commercial Officer | Oct 02 '25 | Sale | 452.05 | 1,405 | 635,127 | 27,438 | Oct 03 |
| ALNY | Tanguler Tolga | EVP, Chief Commercial Officer | Aug 29 '25 | Sale | 448.37 | 3,474 | 1,557,649 | 25,992 | Sep 02 |
| ALNY | Tanguler Tolga | EVP, Chief Commercial Officer | Aug 18 '25 | Sale | 453.27 | 1,396 | 632,759 | 29,466 | Aug 19 |