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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| SYRE | Sloan Sheldon | Chief Medical Officer | Jul 01 '26 | Option Exercise | 27.46 | 8,334 | 228,852 | 8,334 | Jul 02 |
| SYRE | Sloan Sheldon | Chief Medical Officer | Jul 01 '26 | Sale | 87.70 | 8,334 | 730,896 | 0 | Jul 02 |
| SYRE | Sloan Sheldon | Chief Medical Officer | Jun 03 '26 | Option Exercise | 27.46 | 8,333 | 228,824 | 8,333 | Jun 03 |
| SYRE | Sloan Sheldon | Chief Medical Officer | Jun 03 '26 | Sale | 75.00 | 8,333 | 624,975 | 0 | Jun 03 |
| SYRE | Sloan Sheldon | Chief Medical Officer | May 01 '26 | Option Exercise | 27.46 | 78,333 | 2,151,024 | 78,333 | May 01 |
| SYRE | Sloan Sheldon | Chief Medical Officer | May 01 '26 | Sale | 71.50 | 78,333 | 5,600,700 | 0 | May 01 |
| SYRE | Sloan Sheldon | Chief Medical Officer | Apr 01 '26 | Option Exercise | 21.66 | 7,958 | 172,370 | 7,958 | Apr 03 |
| SYRE | Sloan Sheldon | Chief Medical Officer | Apr 01 '26 | Sale | 50.00 | 7,958 | 397,900 | 0 | Apr 03 |