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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| AGIO | Scadden David | Director | Jun 18 '26 | Option Exercise | 0.00 | 2,816 | 0 | 20,419 | Jun 23 |
| AGIO | Scadden David | Director | Nov 12 '25 | Option Exercise | 18.09 | 200 | 3,618 | 17,803 | Nov 14 |
| AGIO | Scadden David | Director | Nov 12 '25 | Sale | 43.84 | 200 | 8,768 | 17,603 | Nov 14 |
| AGIO | Scadden David | Director | Oct 08 '25 | Option Exercise | 18.09 | 200 | 3,618 | 17,803 | Oct 10 |
| AGIO | Scadden David | Director | Oct 08 '25 | Sale | 41.00 | 200 | 8,200 | 17,603 | Oct 10 |
| AGIO | Scadden David | Director | Sep 30 '25 | Option Exercise | 18.09 | 200 | 3,618 | 17,803 | Oct 02 |
| AGIO | Scadden David | Director | Sep 30 '25 | Sale | 40.00 | 200 | 8,000 | 17,603 | Oct 02 |
| AGIO | Scadden David | Director | Aug 27 '25 | Option Exercise | 18.09 | 200 | 3,618 | 17,803 | Aug 29 |
| AGIO | Scadden David | Director | Aug 27 '25 | Sale | 40.00 | 200 | 8,000 | 17,603 | Aug 29 |
| AGIO | Scadden David | Director | Jul 10 '25 | Option Exercise | 18.09 | 1,400 | 25,326 | 19,003 | Jul 15 |
| AGIO | Scadden David | Director | Jul 10 '25 | Sale | 40.00 | 1,400 | 56,000 | 17,603 | Jul 15 |
| AGIO | Scadden David | Director | Jun 20 '25 | Option Exercise | 0.00 | 2,120 | 0 | 17,603 | Jun 23 |
| AGIO | Scadden David | Director | Dec 11 '24 | Option Exercise | 18.09 | 200 | 3,618 | 15,683 | Dec 13 |
| AGIO | Scadden David | Director | Dec 11 '24 | Sale | 46.28 | 200 | 9,256 | 15,483 | Dec 13 |
| AGIO | Scadden David | Director | Jun 13 '24 | Option Exercise | 0.00 | 3,388 | 0 | 15,483 | Jun 17 |