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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| KRYS | Krishnan Suma | President, R&D | Jun 04 '26 | Sale | 308.11 | 25,000 | 7,702,826 | 1,378,155 | Jun 05 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Mar 04 '26 | Sale | 263.21 | 25,000 | 6,580,269 | 1,403,155 | Mar 06 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Feb 27 '26 | Option Exercise | 0.00 | 93,725 | 0 | 1,509,075 | Mar 03 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Dec 04 '25 | Sale | 220.15 | 50,000 | 11,007,336 | 1,413,711 | Dec 05 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Jul 16 '25 | Sale | 150.00 | 2,918 | 437,700 | 1,438,711 | Jul 16 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Jul 15 '25 | Sale | 150.99 | 6,120 | 924,061 | 1,440,240 | Jul 16 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Jul 14 '25 | Sale | 150.30 | 26,835 | 4,033,240 | 1,443,276 | Jul 16 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Jul 10 '25 | Sale | 150.27 | 13,727 | 2,062,793 | 1,456,711 | Jul 11 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Jul 09 '25 | Sale | 150.10 | 400 | 60,042 | 1,463,511 | Jul 11 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Mar 13 '25 | Sale | 177.79 | 50,000 | 8,889,525 | 1,463,711 | Mar 13 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Feb 28 '25 | Option Exercise | 0.00 | 107,500 | 0 | 1,574,926 | Feb 28 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Dec 13 '24 | Sale | 164.80 | 50,000 | 8,240,024 | 1,475,882 | Dec 13 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Sep 12 '24 | Sale | 197.77 | 50,000 | 9,888,278 | 1,500,882 | Sep 13 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Jun 11 '24 | Sale | 175.76 | 50,000 | 8,788,061 | 1,525,882 | Jun 11 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Mar 11 '24 | Sale | 170.95 | 50,000 | 8,547,720 | 1,550,882 | Mar 11 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Feb 28 '24 | Option Exercise | 0.00 | 27,500 | 0 | 1,643,047 | Mar 01 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Dec 11 '23 | Sale | 105.67 | 50,000 | 5,283,291 | 1,574,206 | Dec 12 12:00 AM |
| KRYS | Krishnan Suma | President, R&D | Sep 11 '23 | Sale | 125.94 | 12,333 | 1,553,219 | 1,672,005 | Sep 12 12:00 AM |