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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| RARE | KAKKIS EMIL D | President & CEO | Mar 02 '26 | Sale | 22.80 | 54,404 | 1,240,411 | 658,994 | Mar 03 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Mar 03 '25 | Sale | 42.10 | 73,434 | 3,091,571 | 641,731 | Mar 04 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Feb 28 '25 | Sale | 42.48 | 25,000 | 1,062,000 | 2,158,985 | Mar 04 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Dec 30 '24 | Sale | 42.23 | 11,727 | 495,231 | 2,183,985 | Dec 31 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Dec 10 '24 | Sale | 50.00 | 8,273 | 413,650 | 2,195,712 | Dec 11 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Sep 03 '24 | Sale | 55.85 | 20,000 | 1,117,000 | 2,223,985 | Sep 05 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Aug 06 '24 | Sale | 50.17 | 20,000 | 1,003,400 | 2,243,985 | Aug 07 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Feb 07 '24 | Sale | 45.00 | 30,000 | 1,350,000 | 539,770 | Feb 08 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Dec 29 '23 | Sale | 47.87 | 30,000 | 1,436,100 | 569,770 | Jan 02 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Oct 19 '23 | Option Exercise | 6.86 | 95,706 | 656,544 | 647,029 | Oct 23 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Oct 19 '23 | Sale | 33.52 | 47,853 | 1,604,033 | 599,743 | Oct 23 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Dec 30 '22 | Sale | 45.57 | 19,582 | 892,352 | 541,108 | Jan 03 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | May 03 '21 | Sale | 107.80 | 30,000 | 3,234,000 | 2,259,741 | May 05 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Mar 01 '21 | Sale | 141.80 | 30,000 | 4,254,000 | 2,289,741 | Mar 03 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Jan 04 '21 | Sale | 136.90 | 30,000 | 4,107,000 | 2,329,741 | Jan 05 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Nov 02 '20 | Sale | 96.82 | 30,000 | 2,904,600 | 2,359,741 | Nov 04 12:00 AM |
| RARE | KAKKIS EMIL D | President & CEO | Sep 01 '20 | Sale | 82.63 | 30,000 | 2,478,900 | 2,389,741 | Sep 02 12:00 AM |