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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| AGIO | Jones Cecilia | Chief Financial Officer | Jun 18 '26 | Option Exercise | 0.00 | 3,000 | 0 | 9,000 | Jun 23 |
| AGIO | Jones Cecilia | Chief Financial Officer | Apr 02 '26 | Option Exercise | 0.00 | 8,500 | 0 | 58,139 | Apr 06 |
| AGIO | Jones Cecilia | Chief Financial Officer | Apr 02 '26 | Sale | 34.71 | 3,141 | 109,024 | 54,998 | Apr 06 |
| AGIO | Jones Cecilia | Chief Financial Officer | Mar 02 '26 | Sale | 28.96 | 5,035 | 145,814 | 38,800 | Mar 03 |
| AGIO | Jones Cecilia | Chief Financial Officer | Mar 02 '26 | Option Exercise | 0.00 | 16,969 | 0 | 50,901 | Mar 03 |
| AGIO | Jones Cecilia | Chief Financial Officer | Dec 30 '25 | Sale | 27.09 | 2,932 | 79,428 | 37,394 | Jan 02 |
| AGIO | Jones Cecilia | Chief Financial Officer | Dec 30 '25 | Option Exercise | 0.00 | 6,000 | 0 | 40,326 | Jan 02 |
| AGIO | Jones Cecilia | Chief Financial Officer | Sep 26 '25 | Option Exercise | 0.00 | 7,472 | 0 | 37,521 | Sep 30 |
| AGIO | Jones Cecilia | Chief Financial Officer | Sep 26 '25 | Sale | 36.77 | 3,651 | 134,247 | 33,870 | Sep 30 |
| AGIO | Jones Cecilia | Chief Financial Officer | Jun 24 '25 | Option Exercise | 0.00 | 6,000 | 0 | 31,829 | Jun 26 |
| AGIO | Jones Cecilia | Chief Financial Officer | Jun 24 '25 | Sale | 33.54 | 1,780 | 59,701 | 30,049 | Jun 26 |
| AGIO | Jones Cecilia | Chief Financial Officer | Mar 03 '25 | Sale | 35.54 | 2,275 | 80,854 | 21,843 | Mar 04 |
| AGIO | Jones Cecilia | Chief Financial Officer | Mar 01 '25 | Option Exercise | 0.00 | 7,667 | 0 | 27,510 | Mar 04 |
| AGIO | Jones Cecilia | Chief Financial Officer | Sep 26 '24 | Sale | 49.03 | 2,542 | 124,634 | 20,158 | Sep 30 |
| AGIO | Jones Cecilia | Chief Financial Officer | Sep 26 '24 | Option Exercise | 0.00 | 7,473 | 0 | 22,700 | Sep 30 |
| AGIO | Jones Cecilia | Chief Financial Officer | Mar 05 '24 | Sale | 32.57 | 672 | 21,887 | 14,840 | Mar 05 |
| AGIO | Jones Cecilia | Chief Financial Officer | Mar 01 '24 | Option Exercise | 0.00 | 2,000 | 0 | 15,512 | Mar 05 |
| AGIO | Jones Cecilia | Chief Financial Officer | Jan 24 '24 | Sale | 21.64 | 1,886 | 40,813 | 13,069 | Jan 24 |
| AGIO | Jones Cecilia | Chief Financial Officer | Jan 20 '24 | Option Exercise | 0.00 | 5,380 | 0 | 14,955 | Jan 24 |