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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| AGIO | Jones Cecilia | Chief Financial Officer | Apr 02 '26 | Option Exercise | 0.00 | 17,000 | 0 | 58,139 | Apr 06 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Apr 02 '26 | Sale | 34.71 | 3,141 | 109,024 | 54,998 | Apr 06 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Mar 02 '26 | Option Exercise | 0.00 | 33,938 | 0 | 50,901 | Mar 03 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Mar 02 '26 | Sale | 28.96 | 5,035 | 145,814 | 38,800 | Mar 03 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Dec 30 '25 | Option Exercise | 0.00 | 12,000 | 0 | 40,326 | Jan 02 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Dec 30 '25 | Sale | 27.09 | 2,932 | 79,428 | 37,394 | Jan 02 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Sep 26 '25 | Option Exercise | 0.00 | 14,944 | 0 | 37,521 | Sep 30 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Sep 26 '25 | Sale | 36.77 | 3,651 | 134,247 | 33,870 | Sep 30 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Jun 24 '25 | Option Exercise | 0.00 | 12,000 | 0 | 31,829 | Jun 26 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Jun 24 '25 | Sale | 33.54 | 1,780 | 59,701 | 30,049 | Jun 26 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Mar 03 '25 | Sale | 35.54 | 2,275 | 80,854 | 21,843 | Mar 04 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Mar 01 '25 | Option Exercise | 0.00 | 15,334 | 0 | 27,510 | Mar 04 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Sep 26 '24 | Option Exercise | 0.00 | 14,946 | 0 | 22,700 | Sep 30 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Sep 26 '24 | Sale | 49.03 | 2,542 | 124,634 | 20,158 | Sep 30 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Mar 05 '24 | Sale | 32.57 | 672 | 21,887 | 14,840 | Mar 05 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Mar 01 '24 | Option Exercise | 0.00 | 4,000 | 0 | 15,512 | Mar 05 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Jan 24 '24 | Sale | 21.64 | 1,886 | 40,813 | 13,069 | Jan 24 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Jan 20 '24 | Option Exercise | 0.00 | 10,760 | 0 | 14,955 | Jan 24 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Sep 28 '23 | Sale | 24.79 | 2,179 | 54,017 | 9,575 | Sep 28 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Sep 26 '23 | Option Exercise | 0.00 | 14,944 | 0 | 14,945 | Sep 28 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Jun 30 '23 | Sale | 28.36 | 1,597 | 45,291 | 3,783 | Jun 30 12:00 AM |
| AGIO | Jones Cecilia | Chief Financial Officer | Jun 28 '23 | Option Exercise | 0.00 | 10,760 | 0 | 5,380 | Jun 30 12:00 AM |