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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| ARWR | Hamilton James C | Chief Medical Officer | Apr 23 '26 | Sale | 75.00 | 10,000 | 750,000 | 226,958 | Apr 24 |
| ARWR | Hamilton James C | Chief Medical Officer | Mar 05 '26 | Sale | 64.19 | 10,000 | 641,900 | 236,958 | Mar 09 |
| ARWR | Hamilton James C | Chief Medical Officer | Jan 05 '26 | Sale | 63.11 | 40,164 | 2,534,661 | 171,958 | Jan 05 |
| ARWR | Hamilton James C | Chief Medical Officer | Oct 01 '25 | Sale | 35.00 | 20,000 | 700,000 | 212,122 | Oct 03 |
| ARWR | Hamilton James C | Chief Medical Officer | Sep 12 '25 | Sale | 30.00 | 15,000 | 450,000 | 232,122 | Sep 16 |
| ARWR | Hamilton James C | Chief Medical Officer | Sep 02 '25 | Sale | 25.00 | 15,000 | 375,000 | 247,122 | Sep 04 |
| ARWR | Hamilton James C | Chief Medical Officer | Aug 15 '25 | Sale | 20.00 | 9,389 | 187,780 | 262,122 | Aug 15 |
| ARWR | Hamilton James C | Chief Medical Officer | Aug 13 '25 | Sale | 20.00 | 611 | 12,220 | 271,511 | Aug 15 |
| ARWR | Hamilton James C | Chief Discovery/Trans Medicine | Jan 06 '25 | Sale | 19.82 | 32,729 | 648,824 | 272,122 | Jan 07 |
| ARWR | Hamilton James C | Chief Discovery/Trans Medicine | Apr 01 '24 | Sale | 28.03 | 6,000 | 168,180 | 204,851 | Apr 03 |
| ARWR | Hamilton James C | Chief Discovery/Trans Medicine | Jan 12 '24 | Sale | 36.89 | 7,940 | 292,904 | 210,851 | Jan 17 |
| ARWR | Hamilton James C | Jan 05 '24 | Sale | 35.18 | 32,143 | 1,130,748 | 218,791 | Jan 05 | |
| ARWR | Hamilton James C | Jan 03 '24 | Sale | 32.19 | 6,300 | 202,781 | 175,934 | Jan 05 | |
| ARWR | Hamilton James C | Jun 30 '23 | Sale | 35.53 | 3,000 | 106,590 | 188,484 | Jul 05 | |
| ARWR | Hamilton James C | Director | Jan 05 '23 | Sale | 37.40 | 13,803 | 516,232 | 191,484 | Jan 06 |
| ARWR | Hamilton James C | Director | Jan 03 '23 | Sale | 38.38 | 10,338 | 396,738 | 145,287 | Jan 05 |
| ARWR | Hamilton James C | Jan 05 '22 | Sale | 61.72 | 6,250 | 385,773 | 155,625 | Jan 06 | |
| ARWR | Hamilton James C | Jan 04 '22 | Sale | 65.49 | 19,375 | 1,268,819 | 161,875 | Jan 06 | |
| ARWR | Hamilton James C | Jan 14 '21 | Sale | 81.29 | 10,000 | 812,941 | 126,250 | Jan 15 | |
| ARWR | Hamilton James C | Jan 06 '21 | Sale | 72.48 | 19,375 | 1,404,275 | 136,250 | Jan 07 | |
| ARWR | Hamilton James C | Jan 05 '21 | Sale | 72.53 | 19,375 | 1,405,303 | 155,625 | Jan 07 |