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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| AGIO | Goff Brian | Chief Executive Officer | Apr 02 '26 | Option Exercise | 0.00 | 78,056 | 0 | 191,104 | Apr 06 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Apr 02 '26 | Sale | 34.71 | 19,068 | 661,850 | 177,604 | Apr 06 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Mar 02 '26 | Option Exercise | 0.00 | 79,000 | 0 | 170,466 | Mar 03 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Mar 02 '26 | Sale | 28.96 | 18,055 | 522,872 | 147,733 | Mar 03 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Dec 30 '25 | Option Exercise | 0.00 | 76,556 | 0 | 149,333 | Jan 02 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Dec 30 '25 | Sale | 27.09 | 18,703 | 506,665 | 136,583 | Jan 02 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Aug 08 '25 | Sale | 36.67 | 11,085 | 406,487 | 123,528 | Aug 12 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Aug 08 '25 | Option Exercise | 0.00 | 45,382 | 0 | 134,613 | Aug 12 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Jun 24 '25 | Sale | 33.54 | 18,700 | 627,198 | 105,401 | Jun 26 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Jun 24 '25 | Option Exercise | 0.00 | 76,554 | 0 | 118,151 | Jun 26 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Mar 03 '25 | Sale | 35.54 | 12,947 | 460,137 | 83,139 | Mar 04 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Mar 01 '25 | Option Exercise | 0.00 | 53,000 | 0 | 101,139 | Mar 04 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Aug 08 '24 | Option Exercise | 0.00 | 45,382 | 0 | 89,883 | Aug 12 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Aug 08 '24 | Sale | 42.75 | 11,091 | 474,140 | 78,792 | Aug 12 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Jun 05 '24 | Option Exercise | 0.00 | 51,054 | 0 | 79,307 | Jun 07 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Jun 05 '24 | Sale | 48.84 | 12,115 | 591,697 | 67,192 | Jun 07 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Mar 05 '24 | Sale | 32.57 | 4,156 | 135,361 | 53,780 | Mar 05 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Mar 01 '24 | Option Exercise | 0.00 | 17,000 | 0 | 57,936 | Mar 05 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Jan 24 '24 | Sale | 21.64 | 7,635 | 165,221 | 49,436 | Jan 24 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Jan 20 '24 | Option Exercise | 0.00 | 34,036 | 0 | 102,110 | Jan 24 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Jan 09 '24 | Sale | 22.99 | 12,066 | 277,397 | 40,053 | Jan 09 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Jan 05 '24 | Option Exercise | 0.00 | 51,054 | 0 | 119,128 | Jan 09 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Aug 08 '23 | Option Exercise | 0.00 | 45,382 | 0 | 45,382 | Aug 10 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Aug 08 '23 | Sale | 25.48 | 10,178 | 259,335 | 26,592 | Aug 10 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Jun 30 '23 | Sale | 28.36 | 11,449 | 324,694 | 14,079 | Jun 30 12:00 AM |
| AGIO | Goff Brian | Chief Executive Officer | Jun 28 '23 | Option Exercise | 0.00 | 51,056 | 0 | 144,655 | Jun 30 12:00 AM |