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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| ALNY | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Mar 05 '26 | Sale | 323.98 | 658 | 213,177 | 20,569 | Mar 06 12:00 AM |
| ALNY | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Mar 04 '26 | Sale | 323.08 | 633 | 204,508 | 21,227 | Mar 06 12:00 AM |
| ALNY | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Mar 03 '26 | Sale | 319.73 | 1,652 | 528,189 | 21,860 | Mar 04 12:00 AM |
| ALNY | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Mar 02 '26 | Sale | 327.65 | 1,598 | 523,584 | 23,512 | Mar 04 12:00 AM |
| ALNY | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Feb 17 '26 | Sale | 331.96 | 2,041 | 677,532 | 21,264 | Feb 17 12:00 AM |
| ALNY | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Feb 13 '26 | Sale | 310.08 | 1,959 | 607,448 | 23,305 | Feb 17 12:00 AM |
| ALNY | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Jan 13 '26 | Sale | 370.33 | 2,290 | 848,063 | 21,264 | Jan 14 12:00 AM |
| ALNY | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Jan 12 '26 | Sale | 362.87 | 1,510 | 547,927 | 23,554 | Jan 14 12:00 AM |
| ALNY | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Nov 17 '25 | Option Exercise | 119.13 | 16,322 | 1,944,440 | 33,392 | Nov 19 12:00 AM |
| ALNY | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Nov 17 '25 | Sale | 452.18 | 12,128 | 5,483,991 | 21,264 | Nov 19 12:00 AM |
| ALNY | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Oct 02 '25 | Sale | 452.05 | 2,441 | 1,103,452 | 25,231 | Oct 03 12:00 AM |
| ALNY | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Aug 18 '25 | Sale | 449.33 | 129 | 57,964 | 23,986 | Aug 19 12:00 AM |