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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Mar 10 '26 | Option Exercise | 229.39 | 105 | 24,086 | 105 | Mar 11 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Mar 10 '26 | Sale | 493.95 | 105 | 51,865 | 0 | Mar 11 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Mar 03 '26 | Sale | 487.18 | 4,728 | 2,303,387 | 409 | Mar 03 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Mar 02 '26 | Option Exercise | 208.90 | 125 | 26,113 | 5,262 | Mar 03 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Mar 02 '26 | Sale | 492.59 | 125 | 61,574 | 5,137 | Mar 03 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Feb 28 '26 | Option Exercise | 0.00 | 9,380 | 0 | 9,292 | Mar 02 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Feb 27 '26 | Sale | 499.71 | 2,345 | 1,171,820 | 409 | Mar 02 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Feb 26 '26 | Option Exercise | 0.00 | 4,654 | 0 | 3,549 | Feb 27 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Feb 11 '26 | Sale | 494.96 | 421 | 208,378 | 409 | Feb 11 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Feb 10 '26 | Option Exercise | 25.54 | 943 | 24,086 | 1,247 | Feb 11 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Feb 10 '26 | Sale | 494.65 | 105 | 51,938 | 830 | Feb 11 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Jan 29 '26 | Option Exercise | 208.90 | 126 | 26,321 | 126 | Jan 30 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Jan 29 '26 | Sale | 520.02 | 126 | 65,523 | 0 | Jan 30 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Jan 27 '26 | Sale | 532.61 | 125 | 66,576 | 0 | Jan 28 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Jan 27 '26 | Option Exercise | 218.25 | 230 | 50,199 | 125 | Jan 28 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Dec 10 '25 | Option Exercise | 229.39 | 104 | 23,857 | 104 | Dec 10 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Dec 10 '25 | Sale | 559.90 | 104 | 58,230 | 0 | Dec 10 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Dec 01 '25 | Option Exercise | 208.90 | 125 | 26,113 | 125 | Dec 02 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Dec 01 '25 | Sale | 568.99 | 125 | 71,124 | 0 | Dec 02 |
| INSP | Curet Myriam | Director | Aug 08 '25 | Sale | 77.28 | 4 | 309 | 3,365 | Nov 24 |
| INSP | Curet Myriam | Director | May 08 '25 | Sale | 153.22 | 2 | 306 | 3,369 | Nov 24 |
| INSP | Curet Myriam | Director | Apr 07 '25 | Buy | 148.26 | 1 | 148 | 3,371 | Nov 24 |
| INSP | Curet Myriam | Director | Mar 20 '25 | Buy | 163.84 | 4 | 655 | 3,370 | Nov 24 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Nov 10 '25 | Sale | 560.00 | 105 | 58,800 | 0 | Nov 12 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Nov 10 '25 | Option Exercise | 229.39 | 105 | 24,086 | 105 | Nov 12 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Oct 29 '25 | Option Exercise | 208.90 | 125 | 26,113 | 125 | Oct 29 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Oct 29 '25 | Sale | 543.00 | 125 | 67,875 | 0 | Oct 29 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Oct 28 '25 | Option Exercise | 234.27 | 7,562 | 1,771,514 | 5,383 | Oct 29 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Oct 28 '25 | Sale | 548.43 | 1,379 | 756,279 | 353 | Oct 29 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Jul 25 '25 | Option Exercise | 242.34 | 4,500 | 1,090,515 | 4,853 | Jul 25 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Jul 25 '25 | Sale | 492.48 | 4,500 | 2,216,160 | 353 | Jul 25 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Apr 25 '25 | Sale | 513.18 | 4,000 | 2,052,720 | 353 | Apr 28 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Apr 25 '25 | Option Exercise | 242.34 | 4,000 | 969,347 | 4,353 | Apr 28 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Mar 03 '25 | Sale | 577.30 | 3,031 | 1,749,783 | 353 | Mar 03 |
| ISRG | Curet Myriam | EVP & Chief Medical Officer | Feb 28 '25 | Option Exercise | 0.00 | 1,002 | 0 | 6,367 | Mar 03 |
| NKTR | Curet Myriam | Director | Sep 18 '23 | Sale | 0.69 | 4,359 | 3,008 | 27,418 | Sep 20 |
| NKTR | Curet Myriam | Director | Sep 23 '22 | Sale | 3.16 | 4,198 | 13,266 | 31,777 | Sep 26 |
| NKTR | Curet Myriam | Director | Sep 22 '21 | Sale | 17.78 | 3,665 | 65,164 | 25,775 | Sep 24 |