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| Ticker | Owner | Relationship | Date | Transaction | Cost | #Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Jan 02 '26 | Sale | 66.10 | 13,187 | 871,703 | 3,792,739 | Jan 05 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 29 '25 | Option Exercise | 6.15 | 51,726 | 318,115 | 3,857,652 | Dec 30 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 29 '25 | Sale | 69.13 | 51,726 | 3,575,575 | 3,805,926 | Dec 30 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 22 '25 | Sale | 68.44 | 12,586 | 861,340 | 3,805,926 | Dec 23 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 19 '25 | Sale | 67.66 | 13,445 | 909,682 | 3,818,512 | Dec 23 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 17 '25 | Sale | 64.04 | 85,000 | 5,443,462 | 3,831,957 | Dec 19 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 16 '25 | Sale | 62.58 | 54,298 | 3,398,186 | 3,916,957 | Dec 16 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 15 '25 | Sale | 68.85 | 130,000 | 8,950,615 | 3,971,255 | Dec 16 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Apr 11 '25 | Sale | 11.49 | 50,800 | 583,692 | 3,921,255 | Apr 11 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Apr 10 '25 | Sale | 10.87 | 50,000 | 543,500 | 3,972,055 | Apr 11 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Apr 09 '25 | Sale | 10.07 | 40,322 | 406,145 | 4,022,055 | Apr 11 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Mar 13 '25 | Sale | 15.07 | 51,425 | 774,975 | 4,062,377 | Mar 17 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Mar 04 '25 | Option Exercise | 7.75 | 133,333 | 1,033,331 | 4,073,802 | Mar 05 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Mar 04 '25 | Sale | 17.02 | 133,333 | 2,269,328 | 3,773,802 | Mar 05 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Mar 03 '25 | Sale | 18.03 | 166,667 | 3,005,006 | 3,907,135 | Mar 05 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Mar 03 '25 | Option Exercise | 7.75 | 300,000 | 2,325,000 | 3,940,469 | Mar 05 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Jan 02 '25 | Sale | 19.05 | 11,520 | 219,456 | 3,764,252 | Jan 06 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 23 '24 | Sale | 19.59 | 12,563 | 246,109 | 3,775,772 | Dec 23 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 18 '24 | Sale | 21.24 | 26,712 | 567,486 | 3,688,335 | Dec 20 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Jan 31 '24 | Option Exercise | 14.54 | 57,499 | 836,035 | 3,772,547 | Feb 02 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Jan 31 '24 | Sale | 32.35 | 57,499 | 1,860,019 | 3,715,048 | Feb 02 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Jan 02 '24 | Sale | 31.01 | 9,952 | 308,637 | 3,715,048 | Jan 04 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 20 '23 | Sale | 28.54 | 12,000 | 342,480 | 3,725,000 | Dec 22 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Oct 25 '23 | Sale | 24.21 | 24,338 | 589,223 | 3,737,000 | Oct 27 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Sep 18 '23 | Option Exercise | 4.75 | 115,310 | 547,722 | 3,819,093 | Sep 20 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Sep 18 '23 | Sale | 28.12 | 57,755 | 1,624,223 | 3,761,338 | Sep 20 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | May 04 '23 | Option Exercise | 2.01 | 50,000 | 100,500 | 3,811,338 | May 05 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | May 04 '23 | Sale | 39.52 | 50,000 | 1,975,792 | 3,761,338 | May 05 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | May 03 '23 | Sale | 39.14 | 54,928 | 2,149,882 | 3,761,338 | May 05 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | May 03 '23 | Option Exercise | 2.01 | 54,928 | 110,405 | 3,816,266 | May 05 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Sep 27 '22 | Option Exercise | 30.79 | 40,624 | 1,250,679 | 3,469,856 | Sep 29 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Jul 07 '22 | Option Exercise | 14.54 | 2,501 | 36,365 | 4,060,135 | Jul 11 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Feb 11 '22 | Option Exercise | 5.19 | 146,388 | 759,754 | 4,204,022 | Feb 14 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Feb 11 '22 | Sale | 51.91 | 146,388 | 7,598,865 | 4,057,634 | Feb 14 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Jan 07 '22 | Option Exercise | 5.19 | 11,806 | 61,273 | 4,057,634 | Jan 07 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 23 '21 | Option Exercise | 5.19 | 11,806 | 61,273 | 3,245,828 | Dec 23 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 15 '21 | Sale | 67.56 | 60,000 | 4,053,432 | 3,219,022 | Dec 17 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Oct 22 '21 | Sale | 65.63 | 50,000 | 3,281,532 | 3,279,022 | Oct 22 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Oct 20 '21 | Sale | 66.23 | 15,000 | 993,450 | 3,329,022 | Oct 22 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 18 '20 | Option Exercise | 5.73 | 40,510 | 232,006 | 2,545,747 | Dec 22 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 09 '20 | Sale | 69.06 | 38,676 | 2,670,806 | 2,505,237 | Dec 10 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 09 '20 | Option Exercise | 2.01 | 38,676 | 77,739 | 2,543,913 | Dec 10 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 08 '20 | Sale | 67.97 | 16,324 | 1,109,542 | 2,505,237 | Dec 10 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Dec 08 '20 | Option Exercise | 2.01 | 16,324 | 32,811 | 2,521,561 | Dec 10 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Oct 23 '20 | Sale | 58.21 | 100,000 | 5,821,031 | 2,505,237 | Oct 23 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Aug 13 '20 | Option Exercise | 9.90 | 50,000 | 495,000 | 2,655,237 | Aug 14 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Aug 13 '20 | Sale | 41.35 | 50,000 | 2,067,500 | 2,605,237 | Aug 14 |
| ARWR | Anzalone Christopher Richard | Chief Executive Officer | Jun 25 '20 | Sale | 38.81 | 200,000 | 7,762,034 | 2,605,237 | Jun 26 |